Frank Lampard will miss at least two weeks with the calf injury he picked up in the midweek Champions League defeat to Shakhtar Donetsk.
The 34-year-old midfielder had to be substituted midway through the first half as the European champions lost 2-1 to the Ukrainian side.
Chelsea boss Roberto Di Matteo confirmed on Friday that Lampard would be out for a couple of weeks, meaning he will initially miss the back-to-back games against Manchester United including Sunday's Barclays Premier League clash at Stamford Bridge.